Syllabus for CHEM 87901 Molecular Biophysics, Fall 2003

 
9/2:  	Room C196.03
      	INTRODUCTION.  Assignment of proteins, Literature searching, PDB, Visualization
	Instructor: Lazaridis
	Homework Assignment: Read Branden & Tooze, Chapters 1,2,12.
	Do the literature search exercise.
	Start compiling the literature on the assigned membrane protein.

9/9:  	Room 3309.
	Introduction to membrane proteins
      	Structure and function of membranes. A case study using fluorescence methods.
	Instructors: Haines, Davenport
	Homework Assignment: Continue compiling the literature on the assigned
	membrane protein. Find the PDB structure of the assigned protein.
	Do the exercise on PDB and RasMol.

9/16:  Function. Biophysical assays of membrane protein function.
	Instructor: Gunner
	Hand in literature search and RasMol exercise
	Homework assignment: Work on report and presentation on the function 
	of the assigned protein.

9/23: Protein Isolation & Purification
	Instructors: Calhoun, Gilchrist
	Homework assignment: Prepare a two-page report and a 20-minute 
	presentation on functional assays and isolation of the assigned protein.

9/30:  Function and Isolation (student presentations)
	Homework assignment: Read Branden & Tooze Chapter 18.  Start working on 
	the structure of the assigned protein.

10/14: Structural Genomics, Proteomics, Sequence analysis
	Instructors: Andras Fiser (AECOM)
	Homework assignment: Start working on the sequence analysis of the 
	assigned protein

10/21: 	Structural Genomics, Proteomics (student presentations)
	Introduction to the format of grant proposals 
	Homework: Read sample grant proposal. Read Branden & Tooze Chapter 17.

10/28:  Structure
	Spectroscopic methods of structure determination. Case study of a 
	G-coupled protein receptor
	Instructors: F. Naider, R. Stark

11/4: Structure (student presentations)

11/11: Computations 
	Instructors: Gunner, Lazaridis
 
11/18: Mini-symposium:
	Speakers: Harel Weinstein, David Eliezer
	Takes place at College of Staten Island.

11/25:  Computations (student presentations)
	Homework: Prepare the final seminar on the assigned protein.

12/2: Final presentations by students
	Homework: Finish work on the final paper.

12/9: Final presentations by students
	Homework: Submit final papers by December 20.