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COURSE SYLLABUS
A: LECTURES
INSTRUCTOR: Professor Teresa J. Bandosz
office : J-1316;  Telephone:
(212) 650-6017; E-mail:
tbandosz@scisun.sci.ccny.cuny.edu
Blackboard site: http://online.cuny.edyu:8001
CONSULTING HOURS:
Tuesday, and Thursday: 11-12 or by appointment.
TEXT BOOK: Analytical Chemistry: D.A.Skoog;
D. M. West; F. J. Holler, S.R. Crouch, 7th edition, 1999.
PREREQUISITES: General Chemistry
GENERAL OBJECTIVE:
This course
intends to introduce the bases of analytical chemistry for chemistry and
biochemistry majors. The emphasis is put either on understanding the theoretical
aspects of quantitative analysis or problem solving skills.
LEARNING GOALS:
Students should:
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Know the physical bases for
analytical methods discussed during the course and understand them |
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Be aware of the sources of
errors and have knowledge how to avoid them |
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Know how to calculate the
amount of analyte in the specific application of each method |
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Know how to obtain calibration
curve and how to use it for an analytical purpose |
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Know the criteria which are
used for choosing the methods for a particular analysis. |
CONCEPTUAL THINKING OBJECTIVES:
| Reading: cause-effect
logic, hypothesis testing, summarizing logic |
| Writing:
cause-effect links, objective designing, experiment planning |
| Data analysis:
relevant data sources, data treatment, qualitative and quantitative
evaluation, data consistency, error analysis |
| Models:
cause-effect, correlation, trends |
LEARNING ACTIVITIES:
HOME ASSIGNMENT:
The course
requires extensive reading and understanding of each chapter covered during the
lecture. Students are encouraged to solve the problems and find answers to all
theoretical questions after each chapter.
QUIZZES: Before each lecture starts the students
will be asked to find an answer to one question or solve the problem (5 minute
quiz) dealing with the material discussed during the previous lecture. The
grading from quizzes will consist of 5% of the total grade.
ATTENDANCE: Students are required to attend all
lectures and laboratories. After 3 absences the instructor will ask the
Registrar to withdraw the student form the course with WU.
GRADING:
No INCOMPLETE
Grade
| Final - 35% |
| Laboratory 30% |
| Examinations 30% |
| Quizzes 05% |
| Workshop up to 5% |
|
To arrange a make up of an exam a note from a
doctor,
etc. HAS TO be shown.
A: SCHEDULE OF LECTURES
DATE; CHAPTERS and High Priority Areas
Jan. 29 5, 6: Introduction, Errors in Chem.
Analysis, Random Errors in Analyses
| types of errors |
| sources of errors |
| standard deviation, variation |
Jan. 31 7: Application of Statistics to
Data Treatment
| t-test |
| Q-test |
| least square method to derive
calibration curve |
Feb. 5 11: Titrimetric Methods of Analysis
| the principles of titration (definitions
of terms) |
| volumetric calculations |
Feb.7 4: Aqueous Solution Chemistry
| chemical equilibria |
| solubility product |
| common-ion effect |
| acid-base dissociation constants |
Feb.13 9: Effects of Electrolytes on Ionic
Equilibria
| thermodynamic and concentration based
equilibrium constants |
| ionic strength (calculations) |
| salt effect |
| activity and activity coefficient (Debye-Huckel
equation) |
Feb. 14 10: Application of Equilibrium
Calculations to Complex Systems
| steps used for solving complex
equilibrium problems |
| calculation of solubility using mass
balance, charge balance and equilibrium constants |
| separation of ions by precipitation |
Feb.21 EXAMINATION
1
Feb. 26 12: Theory of Neutralization
Titration
| how an indicator work |
| calculations of titration curves for
strong acids and strong bases and vice versa |
| definition of buffers, their preparation
and basic calculations (pH, volumes) |
| titration curves for weak acids with
strong bases or weak bases with strong acids |
Feb. 28 13: Titration Curves for Complex
Acid/Base Systems
| titration curves for mixtures of strong
and weak acids (strong and weak bases) |
| buffers based on polyfunctional species |
March 5 13: Titration Curves for Complex
Acid/Base Systems
| titration curves for polyfunctional
acids with understanding of the mechanism of the processes in each pH
range |
March 7 14: Application of Neutralization
Titration
| standards and standardization |
| carbonates and carbonate mixtures |
March 12 15: Precipitation
Titrimetry;:
Complex Formation Titration
| titration curves in precipitation
titration (for individual ions and mixtures) |
| definition of terms in complex formation
titration |
| form of EDTA in solution and their
properties |
| calculations of the metal concentration
based on EDTA titration |
March 14 EXAMINATION
2
March 19 16: Introduction to Electrochemistry
| redox reactions (balance, oxidant, reductant) |
| schematic representation of the
electrochemical cell |
| electrode potentials (standard electrode
potential) |
| electrolytic and galvanic cells |
| Nerst equation |
March 21 17: Application of Standard
Electrode Potential
| thermodynamic potential of the cell and
its determination |
| calculations of redox equilibrium
constants |
| redox titration curves and equilibrium
point potential |
| K constant calculations |
March 26 18: Application of
Oxidation/Reduction Titration
| standard oxidants and reductants |
| their applications |
| calculation based on redox reactions |
March 28 19: Potentiometry
| reference electrodes |
| indicator electrodes |
| diagram of glass/calomel cell for the
measurement of pH and definition of all potential playing role in the
system |
| the principle of working of glass
membrane electrode |
| standard addition method for calculation
of ion concentration based on the cell potential |
| potentiometric titration |
April 2 20: Other electroanalyical methods
| sources of polarization |
| potential selectivity in electrolytic
methods |
| coulometric methods for calculation of
the amount of the analyte |
| comparison of coulometric and
conventional titrations |
| voltammograms, id, E1/2 |
| dependence of limiting current on
concentration |
| calculation of the amount of analyte
based on the diffusion current |
April 4 EXAMINATION
3
April 16 21: Introduction to Spectrochemical
Methods
| properties of electromagnetic radiation |
| electromagnetic spectrum |
| mechanism of absorption of radiation
(atoms and molecules) |
| transmitance and absorbance |
| Beer Law |
April 18 23: Molecular Absorption
Spectroscopy
| mechanism of absorption by organic and
inorganic molecules |
| charge transfer absorption |
| characteristics of spectrophotometic
methods |
| standards addition methods to calculate
the concentration of analyte |
| principles of photometric titration |
April 23 23: IR and atomic spectroscopy
| IR spectroscopy |
| calculation of concentration of
components of the mixture based on the absorption of radiation |
| preparation of samples for measurement |
| function of flame |
| differences between AAS and AFS |
| sources of interferences and how to
avoid them |
April 25 EXAMINATION
4
April 30 24: Analytical separations
| Filtration |
| Distillation |
| Ion exchange |
May 3 24 F: An Introduction to
Chromatographic Methods
| elution in chromatography |
| how to increase separation |
| partition ratio, capacity factor |
| column efficiency: N, H |
| column resolution |
May 7 25A: Gas-Liquid Chromatography
| main parts of GC |
| FIT and TCD |
| properties of solid support |
| types of columns |
May 9 25B,C, 26A: High Performance Liquid
Chromatography
| main parts of LC |
| application of liquid chromatography |
| normal and reverse phase chromatography |
| ion chromatography |
| advantages of SFC over HPLC and GC |
| comparison of GC and HPLC |
May 14 Summary of Analytical Methods
| criteria for choosing an analytical
method |
| steps in sample preparation |
| water in solids |
| methods used for the decomposition of
samples |
FINAL-covers all material
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created
by TJB. last
updated: May 29, 2002 updated
by Thiri
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