The New York Structural Biology Center

The New York Structural Biology Center (NYSBC) is a state-of-the-art research center being developed cooperatively by nine outstanding research centers.

The Center will house the largest and most advanced cluster of high-field research magnets (NMRs) in the United States in its first phase. The second phase will include state-of-the-art cryo Electron Microscopes and sample preparation resources.

NYSBC web page


Cryo-electron microscopy

From the Nieder Lab at Berkeley "EM for Dummies" (yes really)

Vaults: large cytoplasmic ribonucleoprotein (RNP) particles found in eukaryotic cells

Examples from the Lab of Holger Stark (SNRNPS and Ribosomes)


Nuclear Magnetic Resonance

NMR :Selective absorption of very high-frequency radio waves by certain atomic nucleisubjected to a strong stationary magnetic field. Nuclei that have at least one unpaired proton or neutron act like tiny magnets. When a strong magnetic field acts on such nuclei, it sets them into precession. When the natural frequency of the precessing nuclear magnets corresponds to the frequency of a weak external radio wave striking the material, energy is absorbed by the nuclei at a frequency called the resonant frequency. NMR is used to study the molecular structure of various solids and liquids. Magnetic resonance imaging, or MRI, is a version of NMR used in medicine to view soft tissues of the human body in a hazard-free noninvasive way. (From Britannica Concise)

Gallery of structures determined by NMR (at the National Magnetic Resonance Facility at Madison)

A hypertext book on 'The Basics of NMR' by Joeseph P. Hornak

A site with information about different types of spectroscopy from Wiley


Opportunities in Biophysics at the City University of New York
(NYSBC is located at the CUNY City College campus)